Title:

Lampe Distinguished Professor of Biomedical Engineering

Office Information:

4307 Engineering Building III
Raleigh, NC 27695
NC State University
(919) 515-1049

150A MacNider Hall
Chapel Hill, NC 27599
UNC Chapel Hill
(919) 843-5830

Education:

2014, Honorary Doctorate, Agricultural University of Athens
2000, D.Sc., for Biosensor Technology, Oxford University
1977 D.Phil.. Biochemistry, Oxford University
1972 B.S. Biology-Chemistry, Furman University

Honors
2017, National Inventors Hall of Fame
2012, Presidential Rank of Meritorious Senior Professional, awarded by President Barack H. Obama
2005, National Academy of Engineering, Bioengineering Section, Councillor 2014-2017
2003, Presidential Rank of Distinguished Senior Professional, awarded by President George W. Bush
2003. Christopher Columbus Foundation Homeland Security Award (Biological, Radiological, Nuclear Field)
Elected Fellow: SPIE, AIMBE, AAAS, National Academy of Inventors

Email:

fsligler@ncsu.edu

Research and Publications:

Research Area:  Biomedical Microdevices
Secondary Research Area:  Regenerative Medicine
Research Interests:  microfluidics, tissue on chip, optical analytical devices, biosensors, nanotechnology
Publications:

Cummins, B.M., R. Chinthapatla, B. Lenin, F.S. Ligler, and G.M. Walker (2017) Modular pumps as programmable hydraulic batteries for microfluidic devices. Technology, Online Ready Articles, DOI: 10.1142/S2339547817200011.
Yu, J., C. Qian, Y. Zhang, Z. Cui, Y. Zhu, Q. Shen, F.S. Ligler, J.B. Buse, and Z.Gu (2017) Hypoxia and H2O2 dual-sensitive vesicles for enhanced glucose-responsive insulin delivery. Nano Lett. 17, 733-739.
Neupane, B., F. Chen, Y. Wei, N. Fang, F.S. Ligler, and G. Wang (2016) Nanosecond time resolution study of gold nanorod rotation on liquid-solid interface. ChemPhysChem 17, 2218-2224.
Pacardo, D.B., F.S. Ligler, and Z. Gu (2016) Dual wavelength-triggered gold nanorods for anti-cancer treatment. Methods Mol.Biol., in press.
Cummins, B.M., F.S. Ligler, and G.W. Walker (2016) Point-of-care diagnostics for niche applications. Biotechnol. Adv. 34, 161-176.
Taitt, C.R., G.P. Anderson, and F.S. Ligler (2016) Evanescent wave fluorescence biosensors: advances of the last decade. Biosens.Bioelectron. 76, 103-112.
Giri, B., B. Pandey, B. Neupane, and F.S. Ligler (2016) Signal amplification strategies for microfluidic immunoassays. Trends Analyt. Chem. 79, 326-334.
Roberts, S.A., K.A .DiVito, F.S. Ligler, A.A. Adams, and M.A. Daniele (2016) Microvessel manifold for perfusion and media exchange in three-dimensional cell cultures.  Biomicrofluidics 10, 054109.
Steward, A.J., J.H. Cole, F.S. Ligler, and E.G. Loboa (2016) Mechanical and vascular cues synergistically enhance osteogenesis in human mesenchymal stem cells. Tissue Eng. Part A 22, 997-1005.
Cummins, B.M., F.S. Ligler, and G.W. Walker (2016) Point-of-care diagnostics for niche applications. Biotechnol. Adv. 34, 161-176.
Taitt, C.R., G.P. Anderson, and F.S. Ligler (2016) Evanescent wave fluorescence biosensors: advances of the last decade. Biosens.Bioelectron. 76, 103-112.
Lu, Y., Q. Hu, Y. Lin, D.B. Pacardo, C. Wang, W. Sun, F.S Ligler, M. D. Dickey, and Z. Gu (2015) Transformable liquid-metal nanomedicine. Nat. Commun. 6:10066.
Yu, J., Y. Zhang, Y. Ye, R. DiSanto, W. Sun, D. Ranson, F.S. Ligler, J.B. Buse, and Z. Gu (2015) Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery. Proc. Nat. Acad. Sci. USA 112, 8260-8265.
Pacardo, D.B., B. Neupane, S.M. Rikard, Y. Lu, R. Mo, S.R. Mishra, J.B. Tracy, G. Wang, F.S. Ligler, and Z. Gu (2015) Dual wavelength-activatable gold nanorod complex for synergistic cancer treatment. Nanoscale 7, 12096-12103.
Pacardo, D.B., F.S. Ligler, and Z. Gu (2015) Programmable nanomedicine: synergistic and sequential drug delivery systems. Nanoscale 7, 3381-3391.Daniele, M.A., D.A. Boyd, A.A. Adams, and F.S. Ligler (2015) Microfluidic strategies for design and assembly of microfibers and nanofibers with tissue engineering and regenerative medicine applications. Adv.Healthcare Mater. 4, 11-28.
Neupane, B., T. Jin, L.F. Mellor, E. Loboa, F.S. Ligler, and G. Wang (2015) Continuous-wave stimulated emission depletion microscope for imaging actin cytoskeleton in fixed and live cells. Sensors 15, 24178-24190.
Tang, J., D. Shen, J. Zhang, F.S. Ligler, and K. Cheng (2015) Bispecific antibodies, nanoparticles, and cells: bringing the right cells to get the job done. Expert Opin.Biol.Ther. 15, 1251-1255.
For a completed list of publications and patents, click here.