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Elizabeth Loboa
Elizabeth Loboa
Associate Professor of Biomedical Engineering & Materials Science and Engineering
B.S. Mechanical Engineering, June 1995, University of California, Davis
M.S.E. Biomechanical Engineering, December 1997, Stanford University
Ph.D. Mechanical Engineering, June 2002, Stanford University
www.bme.ncsu.edu/labs/cml
4208B Engineering Building III
NC State University
(919) 513-4015

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Rehabilitation Engineering
Functional Tissue Engineering, Mechanobiology, Stem Cells
Dr. Loboa's research focuses on better understanding the effects of mechanical loads on mesenchymal tissue and mesenchymal stem cell differentiation with an end goal of functionally tissue engineering structurally robust skeletal tissues that can successfully withstand in vivo loading. Currently, her lab is 1) investigating the effects of different levels of tensile strain in promoting osteogenesis of human mesenchymal stem cells (hMSCs)and human adipose derived adult stem cells (hASCs); 2) implementing microfluidics as a high-throughput screening tool for testing multiple shear stresses in promoting osteogenesis of hMSCs and hASCs; 3) investigating the role of palladin in mechanotransduction of hMSCs and hASCs; 4) optimizing the process of converting image data to functional finite element models for pre-distraction/pre-surgical planning prior to distraction osteogenesis procedures; and, 5) investigating the roles of hydrostatic pressure in promoting chondrogenesis of hASCs and hMSCs from both normal and osteoarthritic donors. More detailed descriptions of work being done in Dr. Loboa's lab can be found here.
http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=DetailsSearch&term=loboa+eg