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Anne Marion Taylor
Anne Marion Taylor
Assistant Professor
Postdoc, California Institute of Technology
Ph.D. Biomedical Engineering, University of California, Irvine
B.S. Civil Engineering, B.S. Engineering and Public Policy, Washington University in St. Louis
www.unc.edu/~amt
4340C MBRB
UNC Chapel Hill
(919) 843-8156

...
Microsystems Engineering
Micro-Scale Devices, Microfluidics, Synapse Formation, Synaptic Plasticity, Protein Synthesis
Our lab exploits micro-scale technology and microfluidics as experimental tools to spatially and temporally probe synapses of the CNS. We are also focused on basic science research, using these tools to understand the role of local translation during synapse development and how synapse function is altered following injury and in neurodevelopmental disorders. We are interested in developing therapeutic strategies that have clinical relevance to promote proper synapse re-formation and circuit development.
1. Tayor, A.M.*, Wu, J.R., Tai, H.-C. & Schuman, E.M.* Axonal translation of beta-catenin regulates synaptic vesicle dynamics. Journal of Neuroscience (2013) 33(13): 5584-9 * co-corresponding authors
** highlighted in 'This Week in the Journal'

2. Hallfors, N., Khan, A., Dickey, M.D., & Taylor, A.M. Integration of pre-aligned liquid metal electrodes for neural stimulation within a user-friendly microfluidic platform. Lab on a Chip (2013) 13(4): 522-6

3. Taylor, A.M. & Jeon, N.L. Micro-scale and microfluidic devices for neurobiology. Current Opinion in Neurobiology (2010) 20(5),640-7

4. Taylor, A.M., Dieterich, D.C., Ito, H. T., Kim, S.A. & Schuman, E.M. Microfluidic local perfusion chambers for the visualization and manipulation of synapses. Neuron (2010) 66, 57-68

5. Taylor, A.M., Berchtold, N.C., Perreau, V.M., Tu, C.H., Jeon, N.L. & Cotman, C.W. Axonal mRNA in uninjured and regenerating cortical mammalian axons. Journal of Neuroscience (2009) 29: 4697-4707
** highlighted in 'This Week in the Journal'
** highlighted in 'The Neuroscientist Comments' [Neuroscientist 2009; 15; 414]

6. Taylor, A.M., Blurton-Jones, M., Rhee, S.W., Cribbs, D.H., Cotman, C.W. & Jeon, N.L. A microfluidic culture platform for CNS axonal injury, regeneration and transport. Nature Methods (2005) 2(8):599-605
** cover illustration