Tissue Engineering Fundamentals (BME 590G): This course introduces the essential concepts of organ and tissue design using living cellular components, including purely cell-based systems and cells in combination with biomaterials, synthetic materials and/or devices. Topics include (1) in vivo tissue structure and function; (2) Isolation and culture of primary cells and stem cells; principles of cellular differentiation (3) mass transport processes in cell culture systems; (4) design, production and seeding of scaffolds for 3D culture; (5) design of bioreactors to support high-density cell growth; (6) state-of-the-art for engineered skin, pancreas, liver and bone; (7) clinical translation.
Contact Dr. Bernacki for more information.

Tissue Mechanics (BME 790T): Students will examine the development of the various constitutive models used to describe the mechanical behavior of biological tissues and the experimental methods used to measure these properties. This course will concentrate on the properties of structural tissues including bone, cartilage, tendon, intervertebral disc and arteries.
Contact Dr. Mente for more information.

Biomedical Imaging Practicum (BMME 890/018): Students perform hands-on experiments with biomedical imaging systems, including image acquisition, processing, and analysis. Students will work with state-of-the-art systems including optical imaging, ultrasound, x-ray and CT, PET, MRI, and SPECT.
Contact Dr. Dayton for more information.

Reverse-Engineering Biological Networks (BMME 890/012): This course will investigate biomolecular networks and current methods for reverse engineering their structure, dynamics and underlying design principles. Content of the course will be based on current research papers as well as related computational projects.
Contact Dr. Gomez for more information.

Biomedical Instrumentation (BMME 465): Topics include basic electronic circuit design, analysis of medical instrumentation circuits, physiologic transducers (pressure, flow, bioelectric, temperate, and displacement). This course includes a laboratory in which the student builds biomedical devices.
Contact Dr. Knisley for more information.

Biomechanics (BMME505): Fundamental principles of solid and fluid mechanics applied to biological systems. Human gait analysis, joint replacement, testing techniques for biological structures and viscoelastic models are presented. Papers from the current biomechanics literature are discussed.
Contact Dr. Gross for more information.

Microelectrode Techniques (BMME 532): Methods for measurement of cellular transmembrane voltages with microelectrodes are introduced. Basic and technical aspects of the measurements are described. Students fabricate microelectrodes and measure action potentials in living cells.
Contact Dr. Knisley for more information.

Microcontroller Applications II (BMME 581): Problems of interfacing computers with biomedical systems are studied. Students collaborate to develop a new biomedical instrument. Projects have included process control, data acquisition, disk systems interfaces, and DMW interfaces between interconnected computers.
Contact Dr. Goldberg for more information.

Functional Genomics Methods (BMME 770): Lectures in physiology systems and lab techniques covering various functional genomic methods including DNA sequencing, gene arrays, proteomics, confocal microscopy, and imaging modalities.
Contact Dr. Banes for more information.

Systems Physiology II (BMME 790): This is the second semester of the two-semester series intended to provide graduate students with an introduction to systems and organ physiology.
Contact Dr. Tommerdahl for more information.

Information Processing in the CNS (BMME 795): Introduction to methodologies used to characterize: (a) the aggregate behavior of living neural networks; and (b) the changes in that behavior that occurs as a function of stimulus properties, pharmacological manipulations, and other factors that dynamically modify the functional status of the network.
Contact Dr. Tommerdahl for more information.

Rehabilitation Engineering Design (BMME 840): Students will design an assistive technology device to help individuals with disabilities to become more independent. The project will be used in the community when it is completed.
Contact Dr. Goldberg for more information.

Numerical Methods (BMME 860): Emphasis on numerical methods for solving inverse problems relevant to biomedical engineering, Matrix inversion, singular value decomposition, and parameter estimation are covered with an emphasis on application of the methods.
Contact Dr. Favorov for more information.

Biomedical Signal Processing (BME 512): Fundamentals of continuous- and discrete-time signal processing as applied to problems in biomedical instrumentation. Properties of biomedical signals and instruments. Descriptions of random noise and signal processes. Interactions between randombiomedical signals and systems. Wiener filtering. Sampling theory. Discrete-time signal analysis. Applications of Z-transform and discrete Fourier transform. Digital filter design methods for biomedical instruments.
Contact Dr. Lalush for more information.

Bioelectricity (BME 525): Quantitative analysis of excitable membranes and their signals. Students learn how excitable membranes produce electric signals, how to record and interpret those signals and how excitable tissue responds to electrical stimulation. Topics include plasma membrane characteristics, origin of electrical membrane potentials, action potentials, voltage clamp experiments, the Hodgkin-Huxley equations, propagation, subthreshold stimuli, extracellular fields, membrane biophysics, and electrophysiology of the heart. Implementation of a computer model of excitable tissue.
Contact Dr. Cartee for more information.